A pressing need exists for timely, evidence-based information to guide cancer care delivery. Although new cancer diagnostic and treatment interventions are subject to rigorous evaluation in clinical trials, clinicians often use these interventions in a broader spectrum of cancer patients, clinical settings, and disease conditions than found in clinical trials. Moreover, clinical trials are rarely designed to evaluate new interventions on multiple endpoints, detect uncommon adverse events, or assess health outcomes over longer periods of time. Consequently, clinicians and other stakeholders attempting to make evidence-based decisions confront substantial gaps in knowledge about the safety, effectiveness, and appropriateness of cancer diagnostic and treatment interventions as they are actually used in clinical practice. The CAN-DEcIDE is approved as a site to respond to the Agency for Healthcare Research and Quality’s (AHRQ) to conduct comparative effectiveness research in cancer.
Principal Investigator: Michael D. Murray, Pharm.D., M.P.H. (07-10), Til Stürmer, M.D., Ph.D. (10 -12); TASK PI: William Carpenter, Ph.D.
Primary Funding Source: AHRQ
Total Project Period: 9/04/08 – 06/30/12