This review sought to provide evidence for how to best communicate and disseminate evidence, including uncertain evidence to inform health care decisions. A secondary objective was to examine how the effectiveness of communication and dissemination strategies varies across target audiences, namely patients and clinicians. Principal Investigator: Stacey Sheridan, M.D. Funding: AHRQ
Systematic Reviews for the US Preventive Services Task Force
The RTI-UNC EPC will produce new and updated systematic reviews for use by the United States Preventive Services Task Force. The Task Force will use the systematic reviews in assessing the available evidence and making recommendations about screening and preventive health services. Principal Investigator: Daniel E. Jonas, MD, MPH Funding: AHRQ Project Period: October 2012… Read more »
EPC III: Genomic Testing for Risk of Recurrent Cancer
UNC personnel at the RTI-UNC Evidence-based Practice Center (EPC) will collaborate with investigators at RTI to conduct a systematic review of available literature for evidence that testing of molecular markers of the risk of tumor recurrence,
Evidence Synthesis and Translation under Medicaid Modernization Act Section 1013: Area 5 – (1) Care delivery, including management, coordination, and prevention, (2) Behavioral interventions
The RTI-UNC Evidence-based Practice Center (EPC) will complete a range of tasks including topic developments, topic refinements, and comparative effectiveness reviews on topics assigned by the Agency for Healthcare Research and Quality (AHRQ). Area 5 topics include care delivery, management, and coordination, prevention, and behavioral interventions. Principal Investigator: Daniel E. Jonas, MD, MPH Funding: AHRQ… Read more »
Evidence Synthesis and Translation under Medicaid Modernization Act Section 1013: Area 4 – (1) Dementia (including Alzheimer’s Disease), (2) Depression and other mental health disorders
The RTI-UNC Evidence-based Practice Center (EPC) will complete a range of tasks including topic developments, topic refinements, and comparative effectiveness reviews on topics assigned by the Agency for Healthcare Research and Quality (AHRQ). Area 4 topics relate to dementia (including Alzheimer’s Disease), depression, and other mental health disorders. Principal Investigator: Daniel E. Jonas, MD, MPH… Read more »
Evidence-based Practice Centers (EPCs) IV
Evidence-based Practice Centers conduct rigorous systematic reviews, synthesize results of systematic reviews and report the findings, advance the methodology of systematic review, collaborate with partners and perform other related EPC activities.
Development and Application of Contextual Frameworks for Patient-Centered Medical Homes, Process Redesign, and Care Transitions
EPC team will apply and refine the CFIR to identify Conceptual factors and implementation processes that should be examined in research on how, why, and where the selected interventions succeeded in or failed to achieve desired outcomes.
Associate Editor Duties for the EPC
Timothy Carey, M.D., M.P.H. will serve as an associate editor for the EPC, reviewing, editing, and providing comments on EPC reports by other EPCs for AHRQ. Principal Investigator: Timothy S. Carey, M.D., M.P.H. Funding: AHRQ Project Period: 8/1/2013 – 8/31/2017
Use of Research Gaps from Systematic Reviews to Inform Research Priorities
UNC-CH will conduct work to develop and complete a ‘white paper’ with the working title “Use of research gaps from systematic reviews to inform research priorities.’
Non-Financial Conflict of Interest Policies (EHC III Program Editorial Review)
The RTI-UNC EPC will assist AHRQ in review of a selection of national and international non-financial conflict of interest policies that pertain to systematic review.
Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Trial Data and Simulation
he main objectives of this RTI-UNC-CH Evidence-based Practice Center methods project are to contribute to the body of literature on MTC meta-analysis.
An Economic Framework for Evaluating Biomarkers Used to Target CVD Prevention
The team will test a variety of different clinical and policy scenarios and systematically examine the effects of key individual variables on the results.
EPC III, Task Order #10, Demonstration of Health Literacy Precautions Toolkit – Methods Project on Bayesian Mixed Treatment Comparisons. Findings of Bayesian Mixed Treatment Comparison Meta-Analyses: Comparison and Exploration Using Real-World Data and Simulation
The main objectives of this RTI-UNC-CH Evidence-based Practice Center methods project are to contribute to the body of literature on MTC meta-analysis.
EPC III: Otitis Media Topic Refinement and Systematic Review
The RTI/UNC-CH Evidence-based Practice Center will develop the topic protocol and conduct a systematic review of the existing literature on otitis media.
Closing the Quality Gap Series: Medication Adherence Interventions- Comparative Effectiveness
The RTI/UNC-CH Evidence-based Practice Center will develop the topic protocol and conduct a systematic review of the existing literature on quality improvement strategies for prescription medication adherence.