Projects by the RTI-UNC Evidence-based Practice Center

Our current and past projects

The RTI-UNC EPC has produced reports, technology assessments, and peer-reviewed journal articles on a wide range of health care topics for the U.S. Preventive Services Task Force (USPSTF), the Agency for Healthcare Research and Quality (AHRQ) Effective Health Care (EHC) and Technology Assessment Programs, the Drug Effectiveness Review Project (DERP), the Washington State Health Technology Assessment (WA-HTA) Program, and other public and private health care organizations.

In the list below, you can further explore our completed products by year and program (jump to USPSTFAHRQ Technology Assessment Program, EHC, or WA-HTA Technology Assessment Program).

Project nameProject funderProject year
Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: An Updated Systematic Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2020
Screening for High Blood Pressure in Children and Adolescents: Systematic Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2020
Primary Care Interventions to Prevent Child MaltreatmentU.S. Preventive Services Task Force (USPSTF)2018
Screening for Intimate Partner Violence and Elder AbuseU.S. Preventive Services Task Force (USPSTF)2018
Screening for Atrial Fibrillation With ElectrocardiographyU.S. Preventive Services Task Force (USPSTF)2018
Screening for Cardiovascular Disease Risk With ElectrocardiographyU.S. Preventive Services Task Force (USPSTF)2018
Screening to Prevent Osteoporotic FracturesU.S. Preventive Services Task Force (USPSTF)2018
Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: An Evidence Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2018
Folic Acid Supplementation: An Evidence Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2017
Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: An Evidence Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2017
Screening for Obstructive Sleep Apnea in Adults: Evidence Report and Systematic Review for the US Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2017
Vision Screening in Children Ages 6 Months to 5 Years: A Systematic Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2017
Serological Screening for Genital Herpes: An Evidence Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2016
Screening for Major Depressive Disorder Among Children and Adolescents: A Systematic Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2016
Screening for Speech and Language Delays and Disorders in Children Age 5 Years or Younger: A Systematic Review for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2015
Screening for Asymptomatic Carotid Artery Stenosis: A Systematic Review and Meta-Analysis for the U.S. Preventive Services Task ForceU.S. Preventive Services Task Force (USPSTF)2015
Dental Caries PreventionU.S. Preventive Services Task Force (USPSTF)2015
Screening for Suicide Risk in Primary CareU.S. Preventive Services Task Force (USPSTF)2004
Screening for Visual Impairment in Children Younger than Age 5 YearsU.S. Preventive Services Task Force (USPSTF)2004
Screening for Asymptomatic Coronary Artery DiseaseU.S. Preventive Services Task Force (USPSTF)2003
Definition of Treatment-Resistant Depression in the Medicare PopulationAHRQ Technology Assessment Program2018
Technology Assessment of Molecular Pathology Testing for the Estimation of Prognosis for Common CancersAHRQ Technology Assessment Program2014
Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine OriginAHRQ Technology Assessment Program2013
Treatment of Depression in Children and Adolescents: A Systematic ReviewEffective Healthcare Program 2020
Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed CountriesEffective Healthcare Program 2018
Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review UpdateEffective Healthcare Program 2018
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review UpdateEffective Healthcare Program 2018
Strategies To De-escalate Aggressive Behavior in Psychiatric PatientsEffective Healthcare Program 2016
Strategies To Improve Mental Health Care for Children and AdolescentsEffective Healthcare Program 2016
Total Worker Health®Effective Healthcare Program 2016
Management and Outcomes of Binge-Eating DisorderEffective Healthcare Program 2015
Management Strategies To Reduce Psychiatric ReadmissionsEffective Healthcare Program 2015
Nonpharmacological Versus Pharmacological Treatments for Adult Patients With Major Depressive DisorderEffective Healthcare Program 2015
Relationship Between Use of Quality Measures and Improved Outcomes in Serious Mental IllnessEffective Healthcare Program 2015
Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired PneumoniaEffective Healthcare Program 2014
Medication Therapy Management Interventions in Outpatient SettingsEffective Healthcare Program 2014
Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient SettingsEffective Healthcare Program 2014
Transitional Care Interventions To Prevent Readmissions for People With Heart FailureEffective Healthcare Program 2014
Models of Cancer Survivorship CareEffective Healthcare Program2014
Otitis Media With Effusion: Comparative Effectiveness of StrategiesEffective Healthcare Program2013
Interventions for the Prevention of Posttraumatic Stress Disorder (PTSD) in Adults After Exposure to Psychological TraumaEffective Healthcare Program2013
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD)Effective Healthcare Program2013
Child Exposure to Trauma: Comparative Effectiveness of Interventions Addressing MaltreatmentEffective Healthcare Program2013
Child and Adolescent Exposure to Trauma: Comparative Effectiveness of Interventions Addressing Trauma Other Than Maltreatment or Family ViolenceEffective Healthcare Program2013
Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With DementiaEffective Healthcare Program2012
Practice-Based Interventions Addressing Concomitant Depression and Chronic Medical Conditions in the Primary Care SettingEffective Healthcare Program2012
Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol MisuseEffective Healthcare Program2012
Drug Therapy for Rheumatoid Arthritis in Adults: An UpdateEffective Healthcare Program2012
Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 ReportEffective Healthcare Program2012
Nonpharmacologic Interventions for Treatment-Resistant Depression in AdultsEffective Healthcare Program2011
Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression: An Update of the 2007 Comparative Effectiveness ReviewEffective Healthcare Program2011
Enhancing Use and Quality of Colorectal Cancer ScreeningEffective Healthcare Program2010
Outcomes of Community Health Worker InterventionsEffective Healthcare Program2009
Outcomes of Maternal Weight GainEffective Healthcare Program2008
Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in AdultsEffective Healthcare Program2007
Comparative Effectiveness of Second-Generation Antidepressants in the Pharmacologic Treatment of Adult DepressionEffective Healthcare Program2007
Management of Uterine Fibroids: An Update of the EvidenceEffective Healthcare Program2007
Tobacco Use: Prevention, Cessation, and ControlEffective Healthcare Program2006
Management of Eating DisordersEffective Healthcare Program2006
Cesarean Delivery on Maternal RequestEffective Healthcare Program2006
Perinatal Depression: Prevalence, Screening Accuracy, and Screening OutcomesEffective Healthcare Program2005
The Use of Episiotomy in Obstetrical Care: A Systematic ReviewEffective Healthcare Program2005
Community-Based Participatory Research: Assessing the EvidenceEffective Healthcare Program2004
Effectiveness of Antimicrobial Adjuncts to Scaling and Root Planing Therapy for PeriodontitisEffective Healthcare Program2004